**Product Overview**
Manufacturer: Zenyaku Kogyo
Product Name: Shin Jikinin Granules, 16 packets
Medical Drug Classification: Designated Class 2 OTC Drug
Category: OTC Medicine
Pediatric Use Category: Suitable for both adults and children
Dosage Form: Powder, Granules, Powdered medicine
Contents: 16 packets
Product Description: A comprehensive cold remedy containing licorice extract, effective for symptoms such as cough, fever, and headache associated with colds.
JAN Code: 4987305114150
Product Code: 076002582

**Initial and Revised Documentation Dates, Version Number**
Initial Creation: September 1, 1986
Revised: July 2019
Document Version Number: 40848

**Features**
Shin Jikinin Granules is a cold medicine that works well for cough, fever, and headache caused by colds, thanks to ingredients such as dihydrocodeine phosphate (a cough suppressant), acetaminophen (a fever reducer and pain reliever), and licorice (glycyrrhiza) extract with cough and expectorant effects.

**Precautions (Do Not Take If):**
1. Do not take if you fall into any of the following categories:
- (1) Have experienced allergic reactions to this medicine or its ingredients.
- (2) Have experienced asthma or allergic reactions after taking this or other cold or pain relief medicines.
- (3) Under 12 years old.
2. While taking this medicine, do not use any other medications containing:
- Other cold medicines, antipyretic and analgesic drugs, sedatives, cough and expectorant medicines, antihistamines (including nasal allergy medications, motion sickness drugs, allergy medications).
3. Do not operate vehicles or machinery after taking this medicine (may cause drowsiness).
4. Breastfeeding women should not take this medicine or should avoid breastfeeding if they do.
5. Do not consume alcohol before or after taking this medicine.
6. Do not use for long-term continuous use.

**Consultation Before Use:**
1. Consult a doctor, pharmacist, or registered seller before use if you are:
- (1) Under medical or dental treatment.
- (2) Pregnant or suspected to be pregnant.
- (3) Elderly.
- (4) Have experienced allergic reactions to medicines or other substances.
- (5) Have symptoms such as high fever, swelling, difficulty urinating.
- (6) Diagnosed with thyroid disorder, diabetes, heart disease, hypertension, liver disease, kidney disease, gastric or duodenal ulcers, glaucoma, respiratory impairment, obstructive sleep apnea syndrome, obesity.
2. If any of the following symptoms appear after taking the medicine, discontinue immediately and consult a doctor, pharmacist, or registered seller:
- [Related parts: Symptoms]
- Skin: Rash, redness, itching
- Digestive system: Nausea, vomiting, loss of appetite
- Nervous system: Dizziness
- Urinary system: Difficulty urinating
- Others: Excessive decrease in body temperature

Serious rare reactions may occur, and in such cases, seek medical attention immediately:
- **Anaphylactic shock:** Itching, hives, hoarseness, sneezing, throat itching, difficulty breathing, palpitations, altered consciousness immediately after taking.
- **Stevens-Johnson syndrome, Toxic epidermal necrolysis, Acute generalized exanthematous pustulosis:** High fever, eye redness, discharge, lip sores, sore throat, widespread skin rash/redness, small pustules on red skin, persistent fatigue, loss of appetite, or rapid worsening.
- **Drug hypersensitivity syndrome:** Widespread redness, systemic rash, fever, fatigue, swollen lymph nodes (neck, armpits, groin).
- **Liver dysfunction:** Fever, itching, rash, jaundice (yellowing of skin and eyes), dark urine, general fatigue, loss of appetite.
- **Kidney impairment:** Fever, rash, decreased urine output, swelling, fatigue, joint pain, diarrhea.
- **Interstitial pneumonia:** Shortness of breath, difficulty breathing, cough, fever that appears suddenly or persists.
- **Pseudoaldosteronism, Myopathy:** Limb weakness, numbness, stiffness, gradually worsening muscle pain and weakness.
- **Asthma:** Wheezing, whistling sounds, difficulty breathing.
- **Aplastic anemia:** Bruising, nosebleeds, gum bleeding, fever, pallor, fatigue, palpitations, shortness of breath, dizziness, hematuria.
- **Agranulocytosis:** Sudden high fever, chills, sore throat.
- **Respiratory depression:** Shortness of breath, difficulty breathing.

3. If any of the following symptoms occur or worsen, stop taking the medicine and consult a healthcare professional:
- Constipation, dry mouth, drowsiness.
4. If symptoms do not improve after 5-6 doses, discontinue use and consult a healthcare professional.

**Dosage and Administration**
Take the following amount within 30 minutes after meals as much as possible:

| Age | Dose per administration | Number of times per day |
|-------|---------------------------|-------------------------|
| 15 years and older | 1 packet (1.5g) | 3 times |
| 12 to under 15 years | 2/3 packet | 3 times |
| Under 12 years | Do not use |

**Usage Precautions:**
- For children, use under the supervision of a guardian.
- Take with water or lukewarm water.

**Ingredients and Quantities (per packet 1.5g):**
- Dihydrocodeine phosphate: 8 mg
- dl-Methylephedrine hydrochloride: 20 mg
- Licorice (glycyrrhiza) extract: 150 mg (equivalent to 750 mg of raw drug)
- Acetaminophen: 300 mg
- Chlorpheniramine maleate: 2.5 mg
- Anhydrous caffeine: 25 mg

**Storage and Handling Precautions:**
- Store in a cool, dry place away from direct sunlight.
- Keep out of reach of children.
- Do not transfer to other containers (risk of misuse or quality deterioration).
- If storing leftover from splitting a packet, fold the bag opening and consume within 2 days.
- Do not use products past their expiration date.

**Inquiries:**
Zenyaku Kogyo Customer Consultation Office
Address: 5-6-15 Otsuka, Bunkyo-ku, Tokyo 112-8650
Phone: 03-3946-3610
Hours: 9:00–17:00 (excluding weekends and holidays)

**Packaging Variants (JAN Codes):**
- 10 packets: 4987305114174
- 16 packets: 4987305114150
- 22 packets: 4987305114167

**Manufacturer:**
Zenyaku Kogyo

**Contents:**
16 packets

**Suggested Retail Price:**
2,090 yen (including tax)

**OTC Drug Classification:**
Designated Class 2 OTC Drug

**Poison and Quarantine Drug Category:**
Not classified as poison or quarantine drug

**Agricultural and Veterinary Drug Category:**
Not classified as agricultural or veterinary drug

**Dosage Form Category:**
Granules

**Pediatric Use Category:**
Suitable for both adults and children

**Product Category:**
OTC Medicine

**Disclaimer:**
【Notice】
- The product descriptions above, excluding pricing information, are provided by the manufacturer or the Self-Medication Database Center.
- If you have any questions or concerns about using this medicine, please consult a doctor or pharmacist.
- We assume no responsibility for health damages caused by the use of medicines purchased through this service.

**Self-Medication Tax Deduction:**
Eligible for self-medication tax deduction.