Product Overview
Manufacturer: Kōkando Pharmaceutical Co., Ltd.
Product Name: Adam A Tablets, 24 Tablets
Medical Drug Classification: Designated Class 2 OTC Drug
Category: OTC Medicine
Pediatric Use Category: For Adults (only dosage and usage for persons 15 years and older)
Dosage Form: Tablets, Round Tablets, Capsules
Contents: 24 Tablets
Product Description: For pain and fever

[Expiration Date]
At the time of shipment, the product has at least one year remaining before the expiration date.
JAN Code: 4987343084613
Product Code: 125300911

[Initial and Revision Dates of the Package Insert, Version Number]
Initial Creation: November 2009
Revised: May 2012
KN130705

Please be sure to read this package insert before use.
Also, keep it in a safe place for future reference.

Features
Pain and fever are caused by substances called prostaglandins produced within the body.
Adam A Tablets are small, film-coated tablets containing ibuprofen, which suppresses prostaglandin production and effectively relieves pain and fever.
They also contain allyl isopropyl acetylurea and anhydrous caffeine to enhance their effect.

Precautions (Things Not to Do)
(If ignored, current symptoms may worsen, or side effects and accidents may become more likely)
1. Do not take this medication if you are:
(1) Someone who has had allergic reactions to this drug or its ingredients.
(2) Someone who has experienced asthma after taking this drug or other antipyretic and analgesic medicines or cold medicines.
(3) Children under 15 years old.
(4) Pregnant women within 12 weeks of their expected delivery date.
2. Do not take any other medications such as other antipyretic and analgesic drugs, cold medicines, sedatives, or motion sickness medicines while taking this drug.
3. Do not operate vehicles or machinery after taking this drug. (Drowsiness or other effects may occur.)
4. Do not consume alcohol before or after taking this medication.
5. Do not use for long-term continuous treatment.

Consultation (When to Seek Medical Advice)
1. Before taking this medication, consult a doctor, dentist, pharmacist, or registered seller if you are:
(1) Under medical or dental treatment.
(2) Pregnant or suspected to be pregnant.
(3) Breastfeeding.
(4) Elderly.
(5) Have experienced allergic reactions to medicines or other substances.
(6) Diagnosed with: heart disease, kidney disease, liver disease, systemic lupus erythematosus, mixed connective tissue disease.
(7) Have had illnesses such as gastric or duodenal ulcers, ulcerative colitis, Crohn’s disease.
2. If any of the following symptoms appear after taking the medication, discontinue immediately and consult a doctor, pharmacist, or registered seller, as these may be side effects:
[Related parts] [Symptoms]
Skin: Rash, redness, itching
Digestive system: Nausea, vomiting, loss of appetite, stomach pain, stomach discomfort, mouth ulcers
Nervous system: Dizziness
Others: Blurred vision, tinnitus, swelling
Serious symptoms that may occur rarely include:
- Shock (Anaphylaxis): Itching, hives, hoarseness, sneezing, throat itching, difficulty breathing, palpitations, altered consciousness occurring immediately after taking the drug.
- Stevens-Johnson syndrome / Toxic epidermal necrolysis: High fever, eye redness, eye discharge, lip sores, sore throat, widespread skin rash or redness that persists or worsens rapidly.
- Liver dysfunction: Fever, itching, rash, jaundice (yellowing of skin and eyes), dark urine, general fatigue, loss of appetite.
- Kidney impairment: Reduced urine output, swelling, difficulty breathing, fatigue, nausea, vomiting, blood or protein in urine.
- Aseptic meningitis: Severe headache with neck stiffness, fever, nausea, vomiting. (Commonly reported in patients undergoing treatment for systemic lupus erythematosus or mixed connective tissue disease.)
- Asthma: Wheezing, whistling sounds, difficulty breathing.

3. If any of the following symptoms occur or worsen, stop taking the medication and consult a doctor, pharmacist, or registered seller:
- Drowsiness, constipation, diarrhea.

4. If symptoms do not improve after 5-6 doses, discontinue use and consult a healthcare professional with this package insert.

Efficacy and Effects
- Relief of pain from headache, toothache, menstrual pain, sore throat, joint pain, muscle pain, neuralgia, back pain, shoulder stiffness, post-extraction pain, bruise pain, ear pain, fracture pain, sprain pain, and injury pain.
- Fever reduction during chills and fever.

Usage and Dosage
Take the following amount up to three times a day, avoiding on an empty stomach as much as possible, with water or warm water without chewing. Maintain at least 4 hours between doses.
[Adults (15 years and older)]
- 2 tablets per dose
[Children under 15 years]
- Do not take

[Precautions related to usage and dosage]
(1) Strictly adhere to the prescribed usage and dosage.
(2) How to take tablets:
Push the convex part of the blister pack with your fingertip to break the aluminum foil on the back, then take out the tablet and swallow.
(Accidentally swallowing the tablet whole or improper handling may cause injury to the esophageal mucosa.)

Ingredients and Amounts (per 2 tablets)
- Ibuprofen: 150 mg (relieves fever, headache, joint pain, shoulder stiffness, etc.)
- Allyl isopropyl acetylurea: 60 mg (aids the analgesic effect of ibuprofen)
- Anhydrous caffeine: 80 mg (also helps the analgesic effect)

Additional ingredients include lactose monohydrate, cellulose, hydroxypropyl cellulose, anhydrous silica, croscarmellose sodium, magnesium stearate, hypromellose, titanium dioxide, macrogol, and carnauba wax.

Storage and Handling Precautions
(1) Store in a cool, dry place away from direct sunlight.
(2) Keep out of reach of children.
(3) Do not transfer to other containers to prevent misuse and preserve quality.
(4) Do not use products past their expiration date.

Inquiries
For questions about this product, contact the customer service desk:
Kōkando Pharmaceutical Co., Ltd. Customer Service
2-27 Nagasumoto-dori, Amagasaki, Hyogo Prefecture
Toll-Free: 0120-023520
Weekdays 9:00–17:00 (excluding weekends and holidays)

Packaging (JAN Codes)
- 60 tablets: 4987343084842
- 120 tablets: 4987343084866
- 60 tablets: 4987343084705
- 120 tablets: 4987343084712
- 24 tablets: 4987343084613
- 48 tablets: 4987343084637
- 60 tablets: 4987343084644
- 120 tablets: 4987343084675

Manufacturer: Kōkando Pharmaceutical Co., Ltd.
Contents: 24 tablets × 1 package
Suggested Retail Price: 825 yen (tax included)
OTC Drug Classification: Designated Class 2 OTC Drug
Poison and Quasi-Drug Category: Not classified as poison or quasi-drug
Agricultural and Veterinary Drug Category: Not classified as agricultural or veterinary drug
Dosage Form Category: Tablets
Pediatric Use Category: For Adults (only dosage and usage for persons 15 years and older)
Product Category: OTC Medicine

Disclaimer
【Caution】
- The product descriptions above, excluding price information, are provided by the manufacturer or the Self-Medication Database Center.
- If you have any questions or concerns about using this medicine, be sure to consult a doctor or pharmacist.
- We assume no responsibility for health damages caused by taking medicines purchased through this service.

Self-Medication Tax Deduction
This product qualifies for the self-medication tax deduction system.