This medicine is a designated second-class OTC drug.

In cases such as children, the elderly, and others who fall under contraindications, there is a risk of serious side effects.

Please consult a pharmacist or registered seller for more details.

【Expiration date of the medicine】

We sell products with an expiration date of at least 120 days.

Product category: Designated second-class OTC drug

【Product details of Bufferin Premium (self-medication tax system applicable)】

● Rapid and excellent effect for severe headaches

● Contains four ingredients effective for headaches

● Uses the latest proprietary technology "Quick Attack Tablets (tablet rapid disintegration + ibuprofen rapid dissolution)"

● Contains the gastric mucosa protective ingredient "dried aluminum hydroxide gel"

● Easy-to-swallow small tablets

*Bufferin has products with different active ingredients. The antipyretic and analgesic ingredients in this product are ibuprofen and acetaminophen. When consulting a doctor, dentist, pharmacist, or registered seller, please specify ibuprofen or acetaminophen.

【Indications and effects】

- Pain relief for headache, shoulder stiffness, menstrual pain (dysmenorrhea), lower back pain, joint pain, neuralgia, muscle pain, sore throat, toothache, post-extraction pain, contusion pain, sprain pain, fracture pain, trauma pain, ear pain
- Fever reduction during chills and fever

【Usage and dosage】

- Avoid taking on an empty stomach as much as possible, and maintain a interval of at least 4 hours between doses.
- Take the following amount with water or lukewarm water.

Adults (15 years and older): 2 tablets per dose, up to 3 times a day
Children under 15 years: Do not take

★ Precautions related to usage and dosage

- Strictly observe the usage and dosage.

【Contact information】

Please contact the store where you purchased or the following.

LION Corporation Customer Center

0120-813-752

Hours: 9:00-17:00 (excluding Saturdays, Sundays, and holidays)

LION Corporation

1-3-7 Honjo, Sumida-ku, Tokyo 130-8644

【Ingredients】

(per tablet)

Ibuprofen: 65 mg
Acetaminophen: 65 mg
Anhydrous caffeine: 40 mg
Allylisopropylacetylurea: 30 mg
Dried aluminum hydroxide gel: 35 mg
Additives: cellulose, hydroxypropyl cellulose, lactic acid, D-mannitol, dipotassium phosphate, silicon dioxide, magnesium stearate, partially hydrolyzed polyvinyl alcohol, talc, titanium dioxide, soybean lecithin

【Precautions】

★ Precautions for use

● Do not use if

(1) You have had allergic reactions to this drug or its ingredients

(2) You have experienced asthma caused by this drug or other antipyretic analgesics or cold medicines

(3) Under 15 years old

(4) Pregnant within 12 weeks of expected delivery

● Do not take any of the following medicines while taking this drug

Other antipyretic analgesics, cold medicines, sedatives, motion sickness medicines

● Do not operate vehicles or machinery after taking (may cause drowsiness, etc.)

● Do not drink alcohol before or after taking

● Do not use for long-term continuous use

● Consult a doctor, dentist, pharmacist, or registered seller before use if

(1) You are undergoing medical treatment

(2) You are pregnant or think you might be pregnant

(3) You are breastfeeding

(4) You are elderly

(5) You have had allergic reactions to medicines or other substances

(6) You have been diagnosed with heart disease, kidney disease, liver disease, systemic lupus erythematosus, or mixed connective tissue disease

(7) You have had gastric or duodenal ulcers, ulcerative colitis, or Crohn's disease

● If any of the following symptoms appear after taking, discontinue immediately and consult a doctor, dentist, pharmacist, or registered seller with the product documentation, as there may be side effects:

Skin: rash, redness, itching, bruising
Digestive system: nausea, vomiting, loss of appetite, stomach pain, stomach discomfort, stomatitis, heartburn, indigestion, abdominal pain, diarrhea, bloody stool, gastrointestinal bleeding
Nervous system: dizziness
Circulatory system: palpitations
Respiratory system: shortness of breath
Others: blurred vision, tinnitus, swelling, nosebleeds, gum bleeding, bleeding that is hard to stop, bleeding, back pain, excessive lowering of body temperature, fatigue

In rare cases, severe symptoms such as the following may occur. In such cases, seek medical attention immediately (refer to the detailed symptoms in the explanatory document):

Shock (anaphylaxis)/Stevens-Johnson syndrome, toxic epidermal necrolysis, acute generalized exanthematous pustulosis/liver dysfunction/kidney dysfunction/interstitial pneumonia, aseptic meningitis, asthma, aplastic anemia, agranulocytosis

● After taking, constipation or drowsiness may occur. If these symptoms persist or worsen, stop taking and consult a doctor, pharmacist, or registered seller with the product documentation.

● If symptoms do not improve after 5-6 doses, discontinue use and consult a healthcare professional.

★ Storage and handling precautions

- Store in a cool, dry place away from direct sunlight.
- Keep out of reach of children.
- Do not transfer to other containers (may cause misuse or change in quality).
- Do not use products past the expiration date.
- Do not damage the aluminum foil on the back of the tablets, as it may cause deterioration.

【About the sale of medicines】

1. Medicines can only be purchased by the person themselves. Orders as gifts, etc., cannot be accepted.

2. Due to the nature of medicines, the quantity of the same product per order is limited to one. Please understand in advance.

3. Orders including medicines will be shipped only on weekdays. Please understand.

4. Please check the efficacy, ingredients, etc.

5. When using, be sure to confirm the usage and dosage.

6. Please read the "Precautions for Use" printed on the product box or attached inside before using.

7. Those with allergies, pregnant women, etc., should consult their doctor before purchasing.

8. For inquiries about the use of medicines, our pharmacist will assist.

【Country of origin】

Japan

【Distributor, manufacturer, importer, or seller】

LION Corporation

/(/F267601/F306201/F359302/F330302/)/

LION Corporation

1-3-7 Honjo, Sumida-ku, Tokyo 130-8644 ※Please refer to the product details for contact number.

Advertising responsibility: Akakabe Co., Ltd.

Phone: 072-878-1339

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