●Name: Loxonin S Premium
Content: 24 tablets
Features: ◆ Contains a pain-relieving ingredient (Loxoprofen sodium hydrate) that quickly works on severe pain, combined with allyl isopropyl acetylurea to enhance pain relief effects.
◆ Additionally, contains anhydrous caffeine to assist in pain relief.
◆ Contains magnesium aluminum silicate to protect the stomach mucosa and safeguard the stomach.
◆ Small tablets that are easy to swallow.
Indications and effects: Pain relief for headache, menstrual pain (dysmenorrhea), toothache, post-extraction pain, sore throat, back pain, joint pain, neuralgia, muscle pain, shoulder stiffness, ear pain, bruises, fractures, sprains, trauma pain, and fever reduction.
Usage and dosage: Adults (15 years and older): 2 tablets per dose, up to 2 times a day.
Take with water or lukewarm water, avoiding on an empty stomach if possible, when symptoms appear.
If symptoms reappear, a third dose can be taken. Maintain a interval of at least 4 hours between doses.
Do not take if under 15 years old.

Precautions related to usage and dosage
(1) Strictly observe the usage and dosage.
(2) How to take out tablets
Press firmly on the protrusions of the PTP sheet containing the tablets with your fingertips, tear the aluminum foil on the back, and take out the tablet for consumption. (Accidentally swallowing the sheet directly may cause injury to the esophageal mucosa.)
Ingredients and amounts: This product is a very thin film-coated tablet with a light red color, containing the following ingredients in 2 tablets.
Loxoprofen sodium hydrate: 68.1 mg (60 mg as anhydrous substance)
Allyl isopropyl acetylurea: 60 mg
Anhydrous caffeine: 50 mg
Magnesium aluminum silicate: 100 mg
Additives: lactose, cellulose, hydroxypropyl cellulose, croscarmellose sodium, magnesium stearate, hypromellose, titanium dioxide, talc, ferric oxide (II, III), carnauba wax
Classification: Class 1 drug / Antipyretic and analgesic / Made in Japan
Precautions: Cautions for use
Things you should not do
(Failure to follow may worsen current symptoms or increase the risk of side effects)
Do not take if you are:
(1) Someone who has had allergic reactions to this drug or its ingredients
(2) Someone who has experienced asthma after taking this drug or other antipyretic and analgesic medications or cold medicines
(3) Children under 15 years old
(4) Someone receiving treatment at a medical institution for: stomach or duodenal ulcers, liver disease, kidney disease, heart disease
(5) Someone diagnosed with blood abnormalities such as low red blood cell count (anemia), low platelet count (easy bleeding or bleeding tendency), or low white blood cell count (blood disorders)
(6) Pregnant women within 12 weeks of expected delivery
While taking this medication, do not take other medications such as:
Other antipyretic and analgesic drugs, cold medicines, sedatives, motion sickness medications
Do not operate vehicles or machinery after taking this medication (may cause drowsiness, etc.)
Do not drink alcohol before or after taking this medication.
Do not take continuously for a long period.
If symptoms persist or recur after 3-5 days of use, stop taking and consult a doctor.
Consultation before use
1. Consult a doctor, dentist, or pharmacist before use if you are:
(1) Receiving treatment from a healthcare professional
(2) Pregnant or suspect pregnancy
(3) Breastfeeding
(4) Elderly
(5) Have had allergic reactions to medicines or other substances
(6) Diagnosed with conditions such as: bronchial asthma, ulcerative colitis, Crohn's disease, systemic lupus erythematosus, mixed connective tissue disease
(7) Have had illnesses such as: stomach or duodenal ulcers, liver disease, kidney disease, blood disorders
2. If any of the following symptoms appear after taking, stop immediately and consult a doctor or pharmacist, as they may be side effects:

(1) Symptoms such as excessive decrease in body temperature, collapse (loss of strength), cold limbs (hands and feet cold)
(2) Symptoms such as gastrointestinal ulcers or swelling
Rarely, serious symptoms such as gastrointestinal bleeding (vomiting blood, nausea, abdominal pain, black tarry stools, bloody stools), gastrointestinal perforation (holes in the digestive tract), or stenosis/obstruction of the small or large intestine (nausea, vomiting, abdominal pain, bloating) may occur. Seek medical attention immediately.
(3) If any of the following symptoms appear after taking:
Related parts: Symptoms
Skin: Rash, redness, itching
Digestive system: Abdominal pain, stomach discomfort, loss of appetite, nausea, vomiting, bloating, heartburn, mouth ulcers, indigestion
Circulatory: Elevated blood pressure, palpitations
Nervous system: Drowsiness, numbness, dizziness, headache
Others: Chest pain, fatigue, facial flushing, fever, anemia, hematuria
Rarely, severe symptoms such as shock (anaphylaxis): immediate onset of skin itching, hives, hoarseness, sneezing, throat itching, difficulty breathing, palpitations, altered consciousness; blood disorders: sore throat, fever, general fatigue, paleness of face and eyelids, bleeding tendencies (gum bleeding, nosebleeds), bruising that does not fade when pressed; Stevens-Johnson syndrome: high fever, conjunctivitis, eye discharge, lip sores, sore throat, persistent or rapidly worsening widespread rash and redness; toxic epidermal necrolysis: similar symptoms as Stevens-Johnson, with severe skin detachment; kidney impairment: fever, rash, decreased urine output, swelling, fatigue, joint pain, diarrhea; congestive heart failure: fatigue, palpitations, shortness of breath, chest discomfort, chest pain, dizziness, fainting; interstitial pneumonia: shortness of breath on exertion, cough, fever, sudden or persistent symptoms; liver dysfunction: fever, itching, rash, jaundice, dark urine, fatigue, loss of appetite; rhabdomyolysis: muscle pain, numbness, weakness, dark urine; aseptic meningitis: severe headache with neck stiffness, fever, nausea, vomiting; asthma: wheezing, shortness of breath.
3. After taking, symptoms such as dry mouth, constipation, diarrhea may occur. If these persist or worsen, consult a healthcare professional.
4. If symptoms do not improve after 1-2 doses (other illnesses may be involved), stop taking and consult a doctor, dentist, or pharmacist.
Storage and handling precautions
(1) Store in a cool, dry place away from direct sunlight.
(2) Keep out of reach of children.
(3) Do not transfer to other containers (may cause misuse or change in quality).
(4) Do not use products past the expiration date printed on the package.
Please read the instructions and precautions carefully before use.
Manufacturer: Daiichi Sankyo Healthcare Co., Ltd., 3-14-10 Nihonbashi, Chuo-ku, Tokyo
Customer Service:
Phone: 0120-337-336, Hours: 9:00-17:00 (excluding weekends and holidays)
Advertising responsibility: Akakabe Co., Ltd.
Pharmaceuticals, contact lenses, nursing care, cosmetics, perfumes, diet, health, supplements, food, daily necessities, stationery, daily use.
3．服用後、次の症状があらわれることがありますので、このような症状の持続又は増強が見られた場合には、服用を中止し、文書を持って医師又は薬剤師に相談して下さい。
口のかわき、便秘、下痢
4．1〜2回服用しても症状がよくならない場合（他の疾患の可能性も考えられる）は服用を中止し、文書を持って医師、歯科医師又は薬剤師に相談して下さい。

●保管及び取扱い上の注意
（1）直射日光の当たらない湿気の少ない涼しい所に保管して下さい。
（2）小児の手の届かない所に保管して下さい。
（3）他の容器に入れ替えないで下さい。（誤用の原因になったり品質が変わります）
（4）表示の使用期限を過ぎた製品は使用しないで下さい。
◆本品記載の使用法・使用上の注意をよくお読みの上ご使用下さい。
●製造販売元 ： 第一三共ヘルスケア株式会社 東京都中央区日本橋3-14-10
お客様相談室
電話：0120-337-336 受付時間：9時〜17時(土、日、祝日を除く)
●広告文責：株式会社アカカベ

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