**Product Overview**
Manufacturer: Zeria Shinyaku Kogyo
Product Name: Assinon Z Gastrointestinal Oral Liquid 30 mL × 3 bottles
Drug Classification: Class 1 OTC drug
Category: OTC medicine
Pediatric Use Category: For adults only (dosage and usage are only specified for adults aged 15 and above)
Dosage Form: Drink / Liquid
Contents: 30 mL × 3 bottles
Product Description: Controls excess stomach acid to improve symptoms such as indigestion and heartburn.

**Expiration Date**
At the time of shipment, there is more than one year remaining until the expiration date.
JAN Code: 4987103047018
Product Code: 074802356

**Initial and Revision Dates of the Package Insert**
Initial creation: July 2009
Revisions: None
Please read this document carefully before use. Keep it in a safe place so you can refer to it when needed.

**Features**
- H2 blocker gastrointestinal medication
- For indigestion, heartburn, nausea, and stomach pain
- Controls excess stomach acid to improve symptoms such as indigestion and heartburn
- Single-use type
- Acerola flavor

**Things Not to Do**
(Doing so may worsen current symptoms or increase the risk of side effects or accidents)

1. Do not take this medication if you are:
(1) Someone who has experienced allergic reactions (such as rash, redness, itching, swelling of the throat, eyelids, lips, etc.) caused by H2 blocker drugs like Nizatidine.
(2) Someone receiving treatment or medication for the following conditions at a medical institution:
- Blood disorders, kidney or liver diseases, stomach or duodenal diseases, immune system diseases such as asthma or rheumatoid arthritis, or taking steroids, antibiotics, anticancer drugs, or azole antifungal agents (which may cause leukopenia, thrombocytopenia, etc.).
- If you have kidney or liver disease, drug excretion may be delayed, leading to stronger effects.
- If you are being treated for stomach or duodenal diseases, Nizatidine or similar drugs are likely prescribed, so be cautious of overlapping medication.
(3) Someone with blood abnormalities such as anemia (low red blood cell count), low platelet count (easy bleeding or bleeding tendency), or low white blood cell count.
- Taking this drug may further decrease blood cell counts.
(4) Children under 15 years old and elderly over 80 years old.
(5) Pregnant women, women who are suspected to be pregnant, or breastfeeding women.

2. Do not take this medication concurrently with other gastrointestinal drugs.

**Consultation Before Use**
1. Consult a doctor or pharmacist before taking if you are:
(1) Under medical treatment or taking other medications.
(2) Have experienced allergic reactions to medicines or drugs.
(3) Elderly (65 years or older).
- Generally, physiological functions may decline with age.
(4) Experiencing symptoms such as sore throat, cough, or high fever.
- These symptoms may indicate severe infection or blood abnormalities such as decreased blood cell counts.
- If these symptoms are present before taking the medication, symptoms may worsen, or side effects may be noticed late.
(5) Unexplained weight loss or persistent abdominal pain.
- These may be caused by other underlying conditions.

2. If any of the following symptoms appear after taking the medication, stop immediately and consult a doctor or pharmacist, as they may be side effects:
- Skin: Rash, redness, itching, swelling of the throat, eyelids, lips, etc.
- Nervous system: Headache, drowsiness, dizziness, numbness in hands/feet or lips, confusion.
- Rarely, serious symptoms such as the following may occur due to this or similar drugs. Seek immediate medical attention:
- Shock (anaphylaxis): Symptoms such as itching, hives, hoarseness, sneezing, throat itching, difficulty breathing, palpitations, or altered consciousness occurring immediately after taking.
- Stevens-Johnson syndrome, Toxic epidermal necrolysis: High fever, eye redness, eye discharge, lip sores, sore throat, widespread skin rash or redness that persists or worsens rapidly.
- Liver dysfunction: Fever, itching, rash, jaundice (yellowing of skin and eyes), dark urine, general fatigue, loss of appetite.
- Blood disorders: Sore throat, fever, general fatigue, paleness of face or behind eyelids, easy bleeding (gum bleeding, nosebleeds), bruising that does not fade when pressed.

3. If you accidentally take more than the prescribed dose, stop immediately and consult a doctor or pharmacist with this product.

4. If symptoms such as the following appear or worsen after taking the medication, stop and consult a doctor or pharmacist:
- Constipation, diarrhea, dry mouth, nausea.

**Efficacy and Effects**
- Heartburn, nausea, stomach pain, indigestion
(Contains drugs that antagonize gastric histamine H2 receptors.)

**Precautions Related to Efficacy and Effects**
- Do not use this medication for symptoms other than those listed above.

**Usage and Dosage**
When symptoms such as heartburn, nausea, stomach pain, or indigestion appear, take the following amount at one time:

| Age Group | Dose per administration | Number of times per day |
|--------------|---------------------------|-------------------------|
| Adults (15 to under 80) | 1 bottle (30 mL) | Up to 2 times |
| Children under 15 | Do not use | |
| Elderly (80 and over) | Do not use | |

- Up to 2 times per day.
- If symptoms do not subside after 8 hours, take another 30 mL bottle.
- Stop taking the medication once symptoms improve.
- If no improvement after 3 days of use, stop and consult a doctor or pharmacist.
- Do not continue use for more than 2 weeks.

**Important**
(1) Strictly observe the prescribed usage and dosage.
(2) Avoid alcohol consumption when taking this medication.

**Ingredients and Amounts**
Per 30 mL bottle:
- Nizatidine: 75 mg

Additives: Erythritol, Reduced maltose syrup, Sucralose, Acesulfame K, Trehalose, Butylparaben, Sodium citrate, Flavoring, Ethanol, Vanillin, pH adjusters (2 components)

**Storage and Handling Precautions**
- Store in a cool, dry place away from direct sunlight.
- Keep out of reach of children.
- Do not transfer to other containers (may cause misuse or change in quality).
- Do not use products past the expiration date.

**Additional Information in the Package Insert**
- If symptoms do not improve after 3 days, stop use and consult a doctor or pharmacist.
- Do not use for more than 2 weeks continuously. (*Note: There is a risk of overlooking serious gastrointestinal diseases; see a doctor.)

**Contact Information**
Customer Service Office
10-11 Nihonbashi Kobunacho, Chuo-ku, Tokyo
Phone: 03-3661-2080
Hours: 9:00–17:50 (excluding weekends and holidays)

**Common Product (JAN) Code for Packaging**
30 mL × 3 bottles: 4987103047018

**Manufacturer**
Zeria Shinyaku Kogyo

**Contents**
30 mL × 3 bottles

**Suggested Retail Price**
1026 yen (tax included)

**OTC Drug Classification**
Class 1 OTC drug

**Poison and Quasi-Drug Category**
Not classified as poison or quasi-drug

**Agricultural and Veterinary Drug Category**
Not classified as agricultural or veterinary drug

**Dosage Form Category**
Internal liquid medication

**Pediatric Use Category**
For adults only (dosage and usage only specified for those 15 and above)

**Product Category**
OTC medicine

**Disclaimer**
【Caution】
- The above product description, excluding price information, is provided by the manufacturer or the Self-Medication Database Center.
- If you have any questions or concerns about using this medicine, be sure to consult a doctor or pharmacist.
- We assume no responsibility for health damages caused by taking medicines purchased through this service.

**Self-Medication Tax Deduction Eligible Product**