【Class 2 OTC Drug】
《Product Description》
With One suppositories produce carbon dioxide in a fine bubble state, which acts on the rectum to gently promote bowel movements. After inserting the suppository into the anus, it takes approximately 10 to 30 minutes to take effect.

Precautions for Use
Things you should not do
(If you do not follow these, your current symptoms may worsen or side effects may become more likely)
1. Do not use if:
You have experienced allergic reactions to this product or its ingredients.
2. While using this product, do not take (use) any of the following medicines:
Other laxatives (purgatives, enema medicines)
3. Do not use continuously:
[Repeated use may weaken the effect (so-called "tolerance") and lead to dependence on the medication.]

Consultation
1. Consult a doctor, pharmacist, or registered seller before use if:
(1) You are undergoing medical treatment.
(2) You have experienced allergic reactions to medicines or other substances.
(3) You have the following symptoms:
Severe abdominal pain, nausea, vomiting
2. If any of the following symptoms appear after use, there is a possibility of side effects. Immediately stop use and consult a doctor, pharmacist, or registered seller with this package insert:
Related parts... Symptoms
Digestive system... Diarrhea, residual stool sensation
Rarely, serious symptoms listed below may occur. In such cases, seek medical attention immediately.
Name of symptoms... Symptoms
Shock... Immediately after use, symptoms such as chest tightness, pale face, cold hands and feet, cold sweat, and difficulty breathing may appear.
3. If bowel movements do not occur after 2-3 uses, stop use and consult a doctor, pharmacist, or registered seller with this package insert.

Other precautions for use
Symptoms such as:
Anal irritation, abdominal discomfort, abdominal pain may occur.

Ingredients and quantities
Per piece (2.6g)
Ingredients...Amount...Function
Sodium bicarbonate...0.5g...Generates fine bubble carbon dioxide, promoting intestinal motility.
Disodium hydrogen phosphate anhydrous...0.68g...Assists in the generation of carbon dioxide.
Additives: Light anhydrous silicic acid, soybean lecithin, hard fat

Efficacy and Effects
Relief of constipation

Usage and Dosage
For ages 12 and above, insert 1 piece into the rectum. If the effect is not observed, insert another piece.
Do not use in children under 12 years old.

＜Method of Use＞
1) How to remove and insert the suppository
1. Break off one piece.
2. As shown in the diagram, peel off the suppository container and take out the suppository.
3. Pinch the rear part of the suppository (the thinner end) with clean fingertips, tissue paper, or gauze, and insert it as deeply as possible into the anus from the swollen side. If insertion is difficult, moisten the tip (the swollen side) with a small amount of water to facilitate insertion.
4. While in a semi-crouching position, push in the suppository and then stand up to easily complete insertion.
2) Precautions after insertion
After insertion, vigorous movement may cause the suppository to come out. Avoid vigorous activity until bowel movement occurs.

Precautions regarding usage and dosage
(1) Strictly observe the prescribed usage and dosage.
(2) After use, wait until the urge to defecate becomes strong.
(If you try to defecate immediately after use, only the medication may be expelled, and the effect may not be observed.)
(3) When used by children over 12, it should be used under the guidance and supervision of a guardian.
(4) If the suppository is soft, cool it for a while before use. If it is too hard, leave it at room temperature (below 30°C) until it softens before use.
(5) Use only in the anus.

Storage and Handling Precautions
(1) Store in a cool, dry place at 1-30°C, away from direct sunlight. Unused portions after opening the aluminum bag should be stored in a cool, dry place (1-15°C) away from direct sunlight.
(2) Keep out of reach of children.
(3) When storing, return the suppository with the swollen side down into the aluminum bag, place it in the outer box, and store upright according to the mark.
(4) Do not transfer to other containers (may cause misuse or change in quality).
(5) Do not use products past the expiration date.

Product Inquiry Contact
For inquiries about this product, please contact the store where purchased or the following:
Zeria Pharmaceutical Co., Ltd. Customer Consultation Office
Phone: 03-3661-2080
Hours: 9:00–17:50 (excluding Saturdays, Sundays, and holidays)
Address: 10-11 Nihonbashi Kobunacho, Chuo-ku, Tokyo 103-8351
Manufacturer's Website Name: Homepage
Manufacturer's Website URL: www.zeria.co.jp
Package Insert Version Number: A60PYH0C16

Manufacturing and Sales Address
Kyoto Pharmaceutical Industrial Co., Ltd.
38 Nishinokyo Tsukinomachi, Nakagyo-ku, Kyoto

Product Category
Class 3 OTC drug

Advertising Responsibility: Akakabe Co., Ltd.
Phone: 072-878-1339